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Priority Programme "Next Generation Optogenetics: Tool Development and Application" (SPP1926) Overview of Submitted Proposals

Mechanism, engineering and application of Rhodopsin-guanylyl cyclases

  • Baier, München
  • Elstner, Karlsruhe
  • Hegemann, Berlin
  • Schneider, Freiburg

Optogenetic control of site-specific proteolysis and protein stability

  • Essen, Marburg
  • Taxis, Marburg

Optogenetic stimulation of intracellular Ca2+ release from the endoplasmatic reticulum

  • Gottschalk, Frankfurt
  • Lehnart, Göttingen
  • Sasse, Bonn

A Bacterial Light-Activated RNA-Binding Protein as an Orthogonal Optogenetic Actuator in Eukaryotes

  • Mayer, Bonn
  • Möglich, Bayreuth

Constructing of genetically encoded light-activated K+-channels with fast gating and distinct trafficking properties

  • Thiel, Darmstadt

Photoswitchable Lipids for the Optical Control of Mechanosensitive Ion Channels

  • Bondar, Berlin
  • Heberle, Berlin
  • Trauner, München

Tuning wavelength and G protein specificty of Melanopsin for optogenetic control of G protein signaling pathways.

  • Gerwert, Bochum
  • Herlitze, Bochum

Development and Application of New Optogenetic Tools Targeted to Intracellular Compartments

  • Hegemann, Berlin
  • Rost, Berlin

Optogenetics-assisted identification of the rapid stress receptor in zebrafish

  • Ryu, Mainz

Analyzing the physiological function of cAMP in primary cilia using optogenetics

  • Wachten, Bonn

Red-light-regulated actuators for spatiotemporal control of opsin expression and modulation of cell-cell interactions within the prefrontal circuit during impulse control

  • Diester, Freiburg
  • Möglich, Bayreuth
  • Ruther, Freiburg
  • Zurbriggen, Düsseldorf

Coordination Funds

  • Gottschalk, Frankfurt

Shedding light on myogenesis: using optogenetics to investigate myoblast differentiation and muscle regeneration

  • Kassel, Karlsruhe
  • Di Ventura, Heidelberg

Development of next-generation light-gated inhibitory ion channels to probe somatosensory integration in the Drosophila nociceptive circuit in vivo

  • Soba, Hamburg
  • Wiegert, Hamburg